Changes of Prooxidant-Antioxidant Systems in Experimental Acute Pancreatitis
نویسندگان
چکیده
منابع مشابه
Micro-rheological changes during experimental acute pancreatitis in the rat.
Although microcirculatory disturbances play pivotal role in the pathomechanism of acute pancreatitis (AP), very few papers can be found which had been tested any of hemorheological parameters. The aim of our study was to analyze the hemorheological changes in cerulein-induced experimental acute pancreatitis in rat in two doses (5 and 10 μg/kg, s.c.). Male and female rats were subjected to Contr...
متن کاملComparison of Prooxidant-antioxidant Balance Method with Crocin Method for Determination of Total Prooxidant-antioxidant Capacity
Objective(s) Comparison of prooxidant-antioxidant balance (PAB) assay with crocin assay. Materials and Methods Twenty eight serum samples were chosen, PAB and the total antioxidant capacity were measured by PAB assay and crocin, respectively, and the correlation of both assays, along with their correlation with other clinical and biochemical parameters, were determined. Results A significa...
متن کاملflow cytometric analysis of inflammatory cells in experimental acute pancreatitis
background: accumulating evidence indicates that inflammatory cells migrate into the pancreas tissue and play an important role in the pathogenesis of acute pancreatitis (ap). the aim of this study was to establish a flow cytometric method to enumerate these infiltrating cells in the pancreas of an experimental ap. materials and methods: twelve hours after inducing of ap, mice pancreatic tissue...
متن کاملPathobiology of experimental acute pancreatitis.
Pancreatic duct obstruction, even in the absence of biliary obstruction and/or bile reflux into the pancreatic duct, can trigger acute hemorrhagic necrotizing pancreatitis. The earliest changes are seen within acinar cells. Early derangements in acinar cell biology include inhibition of digestive enzyme secretion and the co-localization of lysosomal hydrolases with digestive enzyme zymogens. Un...
متن کاملnoscapine and acute pancreatitis: effects of different doses of noscapine on serum amylase level in experimental acute pancreatitis in rats
introduction and aims: noscapine has been recently known as an antagonist of bradykinin, and in this study its effect on the animal model of acute pancreatitis has been evaluated. materials and methods: 49 male wistar rats have been evaluated in five experimental and four control groups. common bile duct has been ligated by means of surgery to induce acute pancreatitis in rats. the resulted inf...
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ژورنال
عنوان ژورنال: Galician Medical Journal
سال: 2017
ISSN: 2414-1518
DOI: 10.21802/gmj.2017.3.13